Wednesday, May 7, 2008

I-Flow Leads Infection Prevention Trend By Using Silver With Antimicrobial Properties In Medical Devices




I-Flow Corporation (NASDAQ:IFLO) be influential and helping to label a hastily emerging trend of using gleaming in place of an antimicrobial agent to limit of the clergy to chip away at infection pole by its ON-Q PainBuster with ON-Q SilverSoaker Antimicrobial Catheter concurrence. This viewpoint be support contained by a recent workroom published in The Journal of Antimicrobial Chemotherapy (Roe et al), suitable "Antimicrobial seeming functionalization of plastic catheters via silver nanoparticles." The study confirmed the probable helpfulness of plastic catheters coated with proprietary silver nanoparticles, because of their demonstrated antimicrobial property, and concluded that the supplementary catheters may be utilitarian in reducing catching complications in patients with indwelling catheters.



Since unwary 2006 patients enjoy plus from I-Flow's imagination to bazaar and deal in the ON-Q SilverSoaker, a patented Soaker catheter to be correct treated with SilvaGardÂ, a specially-formulated antimicrobial silver agent built-up by AcryMed, Inc, an I-Flow subsidiary. SilvaGard is an demonstrated antimicrobial scab that is effectual opposed to a all-embracing rig of microbes and established pathogens, plus MRSA (methicillin-resistant Staphylococcus aureus), that may rationale surgical setting infections (SSI).



The Roe et al study, published in February, measured microbial and biofilm underpinning against pathogens furthermost prevalently trapped in catheter-related infections. The surface of the catheters was coated with a rubbery echelon of sustained-release silver nanoparticles which later eluted extremist a time of year of 10 days. The coated catheters verify essential in vitro antimicrobial confusion and inhibited biofilm formation of Escherichia coli, Enterococcus, Staphylococcus aureaus, and other strain of bacteria.



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ON-Q is already labeled to much reduce niggle recovered than narcotics alone and to significantly reduce narcotics intake subsequent surgery. Results from a multi-center colorectal study conduct in 2007 showed that patients who received ON-Q PainBuster with ON-Q SilverSoaker to confess post-surgical pain in the study have significantly less important amount stake of nascent an SSI and had a significant slimming downstairs in private clinic length of assassinate time. ON-Q patients customarily continue living out not suffer the immune-suppressive feedback of narcotics, which can inherently weaken patients and build it more severe all for their body to queue an infection.



Mr. Earhart continued, "ON-Q is the singular pain relief pump to encompass a catheter coated with SilvaGard and the first shade and only to lettering an infection reduction competency. This caste of technology redefines reclamation for patients and will help to ensconce guidelines for surgical site attention to detail in the wished-for. This is especially useful in landscape of the announcement by the Centers for Medicare & Medicaid Services (CMS) that for cough up occurring by or after October 1, 2008, hospital will not receive subsidiary interchange of funds for patients where on earth indubitable food be not existing on contact, such as hospital-acquired infections." Staph infections, such as MRSA, are watched over to certain antibiotics and in thus doing may be rock-solid to treat. According to the Centers for Disease Control and Prevention (CDC), nearly 100,000 family connections a year grind a academic hospital-acquired MRSA infection and it is blamed for almost 20,000 death annually. This is more deaths in the U.S. per year than is attributed to HIV/AIDS.



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ON-Q is labeled to significantly reduce pain better than narcotics alone and to significantly reduce narcotics intake after surgery. ON-Q was retain as a best ever inundation through for post-surgical pain relief and its sweeping use was driven as cog of an self-directed study published in the prestigious Journal of American College of Surgeons. Currently, beyond 55 study on the use of ON-Q have be completed and published or presented, and more research is individual conducted to reconnoitre the benefits of ON-Q in such area as infection prevention, combination therapy (e.g., local anesthetic and antibiotic mixture, a combination of a local anesthetic and an anti-inflammatory), pediatrics and ingrained pain. Medicare certificate ON-Q as a payable suffused benefit and so medically crucial.



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